This report presents conclusion of the APEC Women-Led Start-Up Accelerator Initiative, which aimed to increase female entrepreneurial participation and strengthening business competitiveness of women-led startups by providing female entrepreneurs with trainings and mentorship. The report was prepared to record and disseminate gained knowledge during the implementation of the project, including the contents of the APEC Women-Led Start-Up Training Manual, and the summaries and key takeaways of the APEC Women-Led Start-Up Accelerator Workshops and Forum. Apart from providing reference to future APEC women empowerment projects and events, the initiative and this final report also aim to share relevant experiences on facing challenges and mitigating impact during a global crisis.